The AFC South could be decided Thursday night in Houston. Both teams come into this matchup at 6-4, but Indianapolis holds the edge by virtue of its 30-23 win over the Texans in Week 7. The Texans had won two-straight since that loss, before running into the steamroller that is Baltimore in Sunday’s 41-7 drubbing. After losing two in a row, the Colts got quarterback Jacoby Brissett back and logged a 33-13 win over Jacksonville in what was Indy’s most complete game of the season. Houston comes into this game with a slight edge on offense (400 total yards per game vs. 358), but Indianapolis has the advantage on defense (340 yards allowed per game vs. 391). Houston has been good at home (9-2 in their last 11 games), but one of those losses was to the Colts in the first round of last year’s playoffs. In fact, Indy has won four of the last five over Houston, and the Colts are 9-3-1 against the spread in their previous 13 games against the Texans. While the nature of the Thursday night game also favors the home team, Indy has been solid on the road for bettors – the Colts are 4-1-1 ATS in their last six road contests. Also note that the Week 7 final score was 7.5 points higher than the set over/under total.